Intel 8086 (1978)
This chip was skipped over for the original PC, but was used in a few later computers that didn’t amount to much. It was a true 16-bit processor and talked with its cards via a 16 wire data connection. The chip contained 29,000 transistors and 20 address lines that gave it the ability to talk with up to 1 MB of RAM. What is interesting is that the designers of the time never suspected anyone would ever need more than 1 MB of RAM.